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EANO

Programme

Programme Overview

1. Basic and Translational Research
Chairs: S. Niclou, M.Lorger

  • Molecular Profiling
  • Neuroscience in depth
  • Carcinogenesis in the CNS
  • Tumor microenvironment in the CNS
  • Research methodology  ( ex. vivo and in vitro models, molecular techniques, biochemical techniques, histology and microscopy, molecular diagnostics, flow cytometry, metabolomic, but also clinical research principles)
  • Science of advanced Imaging (fMRI, Tractography, DTI, MRS, MRI perfusion
  • intraoperative monitoring and mapping and preoperative mapping using nTMS)
  • Science of PET imaging (different tracers)
  • Setting up a NO program

2. Gliomas

  • Epidemiology Etiology Genetic Syndromes
  • Diagnosis Radiology/Presentation
  • Neurosurgery high-grade biopsy, maximal safe, gross total, supramaximal resection
  • Neurosurgery low grade
  • Neuro radiotherapy 1st line
  • Chemotherapy and targeted therapy
  • Relapse re-operation
  • Re-radiotherapy
  • 2nd line chemotherapy
  • Monitoring (including Pseudo Progression and Pseudo Response)
  • Neurocognitive evaluation and management
  • End of life and supportive care

Selected topics of Basic Research and Clinical Research:

  • Immunotherapy
  • CART cells, viral vectors, autologous vaccines
  • Novo TTF
  • Issues in Research-Response Criteria and Management

3. Extra axial tumors and CNS lymphoma

  • Meningioma
  • Sella tumors
  • Schwannoma (MPNST)
  • CNS lymphoma
  • Research epidemiology genetics
  • Surgery Radiotherapy, chemotherapy, targeted therapy
  • Long Term sequelae and Quality of Life
  • Selected topics of Basic Research and Clinical Research

4. Pediatric Neuro-Oncology

  • Epidemiology
  • Genetic Syndromes
  • Gliomas including DIPG Surgery Radiotherapy Chemotherapy
  • ATRT Surgery Radiotherapy Chemotherapy
  • Neuroblastoma Surgery Radiotherapy Chemotherapy
  • Monitoring and Late sequelae
  • Psychosocial support, End of Life
  • AYA, TYA special considerations
  • Selected topics of Basic Research and Clinical Research

5 . Rare primary CNS tumors in children and adults

  • Medulloblastoma
  • Ependymoma
  • Glioneuronal tumors
  • Germ cell tumors
  • Ultra rare tumors
  • Epidemiology
  • Molecular biology
  • Surgery, Radiotherapy, Chemotherapy, Targeted therapy
  • Relapse Treatment
  • Monitoring and long-term sequelae
  • Selected topics of Basic Research and Clinical Research

6. Metastases to the CNS (brain and leptomeningeal Dx)

  • 1)      NSCLC
  • 2)      Melanoma
  • 3)      Breast Cancer
  • 4)      Renal
  • 5)      Miscellanea
  • Diagnosis
  • Surgery
  • RT, SRT, radiation necrosis
  • Targeted of therapy, Chemotherapy
  • IT therapy
  • Screening when / in which tumors/ how frequently & how /prevention?
  • Research, Biology, branched evolution divergent mutations
  • Selected topics of Basic Research and Clinical Research

7. Hot Clinical Issues

  • Spinal Cord Tumors
  • Spinal Cord Compression
  • Neurological Side Effects of Cancer Therapies
  • Epilepsy and Neuro Oncology
  • Paraneoplastic Syndromes
  • Principle of Best Supportive Care
  • Communication, patient and caregiver involvement and shared decision making (PRO in NO)
  • Selected topics of Basic Research and Clinical Research