Programme Overview
1. Basic and Translational Research
Chairs: S. Niclou, M.Lorger
- Molecular Profiling
- Neuroscience in depth
- Carcinogenesis in the CNS
- Tumor microenvironment in the CNS
- Research methodology ( ex. vivo and in vitro models, molecular techniques, biochemical techniques, histology and microscopy, molecular diagnostics, flow cytometry, metabolomic, but also clinical research principles)
- Science of advanced Imaging (fMRI, Tractography, DTI, MRS, MRI perfusion
- intraoperative monitoring and mapping and preoperative mapping using nTMS)
- Science of PET imaging (different tracers)
- Setting up a NO program
2. Gliomas
- Epidemiology Etiology Genetic Syndromes
- Diagnosis Radiology/Presentation
- Neurosurgery high-grade biopsy, maximal safe, gross total, supramaximal resection
- Neurosurgery low grade
- Neuro radiotherapy 1st line
- Chemotherapy and targeted therapy
- Relapse re-operation
- Re-radiotherapy
- 2nd line chemotherapy
- Monitoring (including Pseudo Progression and Pseudo Response)
- Neurocognitive evaluation and management
- End of life and supportive care
Selected topics of Basic Research and Clinical Research:
- Immunotherapy
- CART cells, viral vectors, autologous vaccines
- Novo TTF
- Issues in Research-Response Criteria and Management
3. Extra axial tumors and CNS lymphoma
- Meningioma
- Sella tumors
- Schwannoma (MPNST)
- CNS lymphoma
- Research epidemiology genetics
- Surgery Radiotherapy, chemotherapy, targeted therapy
- Long Term sequelae and Quality of Life
- Selected topics of Basic Research and Clinical Research
4. Pediatric Neuro-Oncology
- Epidemiology
- Genetic Syndromes
- Gliomas including DIPG Surgery Radiotherapy Chemotherapy
- ATRT Surgery Radiotherapy Chemotherapy
- Neuroblastoma Surgery Radiotherapy Chemotherapy
- Monitoring and Late sequelae
- Psychosocial support, End of Life
- AYA, TYA special considerations
- Selected topics of Basic Research and Clinical Research
5 . Rare primary CNS tumors in children and adults
- Medulloblastoma
- Ependymoma
- Glioneuronal tumors
- Germ cell tumors
- Ultra rare tumors
- Epidemiology
- Molecular biology
- Surgery, Radiotherapy, Chemotherapy, Targeted therapy
- Relapse Treatment
- Monitoring and long-term sequelae
- Selected topics of Basic Research and Clinical Research
6. Metastases to the CNS (brain and leptomeningeal Dx)
- 1) NSCLC
- 2) Melanoma
- 3) Breast Cancer
- 4) Renal
- 5) Miscellanea
- Diagnosis
- Surgery
- RT, SRT, radiation necrosis
- Targeted of therapy, Chemotherapy
- IT therapy
- Screening when / in which tumors/ how frequently & how /prevention?
- Research, Biology, branched evolution divergent mutations
- Selected topics of Basic Research and Clinical Research
7. Hot Clinical Issues
- Spinal Cord Tumors
- Spinal Cord Compression
- Neurological Side Effects of Cancer Therapies
- Epilepsy and Neuro Oncology
- Paraneoplastic Syndromes
- Principle of Best Supportive Care
- Communication, patient and caregiver involvement and shared decision making (PRO in NO)
- Selected topics of Basic Research and Clinical Research