Diagnosis and treatment of brain metastases from solid tumors: guidelines from the EANO
The management of patients with brain metastases has become a major issue due to the increasing frequency and complexity of the diagnostic and therapeutic approaches. In 2014, the European Association of Neuro-Oncology (EANO) created a multidisciplinary Task Force to draw evidence-based guidelines for patients with brain metastases from solid tumors. Here, we present these guidelines, which provide a consensus review of evidence and recommendations for diagnosis by neuroimaging and neuropathology, staging, prognostic factors, and different treatment options. Specifically, we addressed options such as surgery, stereotactic radiosurgery/stereotactic fractionated radiotherapy, whole-brain radiotherapy, chemotherapy and targeted therapy (with particular attention to brain metastases from non–small cell lung cancer, melanoma and breast and renal cancer), and supportive care.
click here for published version (published in Neuro-Oncology, Volume 19, Issue 2, 1 February 2017, Pages 162–174, https://doi.org/10.1093/neuonc/now241)
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