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Invitation for the General Assembly of EANO
Dear Friends,
You are invited to participate in the General Assembly of EANO on September 18.
Bevacizumab therapy for radiation necrosis of the CNS
The development of effective therapy for CNS radiation necrosis is complicated because the mechanisms of radiation-induced injury are not completely understood. Current opinion is that radiation necrosis is a continuous process from endothelial cell dysfunction to tissue hypoxia and necrosis, with ...
Commentary on the study ‘Randomized Double-Blind Placebo-Controlled Trial of Bevacizumab for Radiation Necrosis of the Central Nervous System’*

By Dr. Damien Ricard, Service de Neurologie,
Hôpital d’Instruction des Armées du Val-de-Grâce, Paris, France.
Focal cerebral and spinal cord radionecrosis, which primarily affects the white matter, is a severe radiation-induced complication which is neuropathologically defined as necrosis with severe vascular lesions (stenosis, thrombosis, haemorrhage, fibrinoid vascular necrosis). Radionecrosis usually develops in the first 2 years after standard conventional RT (for intracranial tumours or head and neck tumours with irradiation fields including temporal lobes of the brain), but can appear decades after treatment.
Mini Symposium on Neuro-Oncology in Eastern European and Northern African Countries
During the EANO Meeting in Maastricht, on September 19, a multidisciplinary Symposium on "Neuro-Oncology in Eastern European and North African Countries" will take place.
The objective is to compare the organization of Neuro-Oncology in Western and non Western countries and establish future forms of cooperation. Speakers from different countries and different professional will give an overview of the status of Neuro-Oncology in their respective countries.
Cytomegalovirus in patients treated with temozolomide
Opportunistic infection by Pneumocystis jiroveci in patients treated with temozolomide have been previously reported, but a recent Brief Report in Clinical Infectious Diseases discusses a series of 6 cases of cytomegalovirus (CMV) disease occurring in patients receiving temozolomide....
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